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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS7
All Species:
14.85
Human Site:
S122
Identified Species:
27.22
UniProt:
O14512
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14512
NP_055413.1
581
62969
S122
L
V
L
E
G
L
E
S
E
A
E
S
L
E
T
Chimpanzee
Pan troglodytes
XP_512211
535
59559
S82
G
T
L
K
R
R
L
S
A
K
Q
K
S
K
G
Rhesus Macaque
Macaca mulatta
XP_001082440
360
39867
Dog
Lupus familis
XP_548159
411
45633
P18
G
R
G
E
Q
Q
Q
P
P
P
P
P
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHQ2
579
62765
S122
L
V
L
E
G
L
E
S
E
A
E
S
L
E
T
Rat
Rattus norvegicus
XP_001081372
564
60962
S108
L
V
L
E
G
L
E
S
E
A
E
S
L
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506079
518
56852
S82
G
S
L
K
R
R
L
S
A
K
Q
K
P
K
G
Chicken
Gallus gallus
XP_423895
264
29931
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684929
733
79803
S271
L
V
L
E
G
L
G
S
E
E
V
N
G
L
G
Tiger Blowfish
Takifugu rubipres
NP_001116335
565
61771
E94
S
I
S
S
L
Q
A
E
L
R
R
Q
V
E
V
Fruit Fly
Dros. melanogaster
NP_523390
1016
110741
C216
L
L
L
A
K
T
E
C
K
L
D
A
L
D
G
Honey Bee
Apis mellifera
XP_397211
804
90105
A246
T
S
G
L
S
H
K
A
D
D
S
S
F
I
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792866
847
94386
R97
R
L
D
N
D
P
E
R
T
S
L
N
G
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
43
69.5
N.A.
97.4
95.1
N.A.
24.1
42.6
N.A.
38.2
52.3
22
24.8
N.A.
27.8
Protein Similarity:
100
36.8
49.5
69.7
N.A.
98.1
95.8
N.A.
34.4
43.7
N.A.
48.2
62.4
32.1
39.2
N.A.
39
P-Site Identity:
100
13.3
0
6.6
N.A.
100
100
N.A.
13.3
0
N.A.
53.3
6.6
26.6
13.3
N.A.
13.3
P-Site Similarity:
100
33.3
0
13.3
N.A.
100
100
N.A.
33.3
0
N.A.
60
20
60
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
8
16
24
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
8
8
8
0
0
8
0
% D
% Glu:
0
0
0
39
0
0
39
8
31
8
24
0
0
31
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
24
0
16
0
31
0
8
0
0
0
0
0
16
0
31
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
16
8
0
8
0
8
16
0
16
0
16
0
% K
% Leu:
39
16
54
8
8
31
16
0
8
8
8
0
31
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
16
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
8
8
8
8
16
8
8
% P
% Gln:
0
0
0
0
8
16
8
0
0
0
16
8
0
0
0
% Q
% Arg:
8
8
0
0
16
16
0
8
0
8
8
0
0
8
0
% R
% Ser:
8
16
8
8
8
0
0
47
0
8
8
31
8
0
0
% S
% Thr:
8
8
0
0
0
8
0
0
8
0
0
0
0
0
39
% T
% Val:
0
31
0
0
0
0
0
0
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _